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Horse Times Magazine :: Winter Issue # 52

PUBLISHED WINTER 2016, ISSUE 52 FEATURES:

THE MOROCCO ROYAL TOUR
TRILOGY OF THE CHAMPIONS

THE 9TH SALON DU CHEVAL D’EL JADIDA
CARRIES A MESSAGE OF REVIVAL TO THE TRADITIONAL EQUESTRIAN ART

JUMPER OF THE YEAR
THE STORY OF BERTRAM ALLEN, A YOUNG JOCKEY WITH EXQUISITE SKILLS

GERMANY TAKE..

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Horse Times Weekly Headlines :: Issue # 24

- FEI WORLD CUP™ VAULTING FINAL 2017: ITALY AND GERMANY TAKE HOME MALE, FEMALE AND PAS-DE-DEUX

- CHI ALSHAQAB 2017: SCOTT BRASH SCOTT BRASH PREVAILS AT THE CSI5* GRAND PRIX

- BOYD EXELL WINS HIS SEVENTH FEI WORLD CUP™ DRIVING TITLE

- ISABELL WERTH WINS IN GOTHENBURG

- VON ECKERMANN SNAT..

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NORWAY 2014

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>> CARDIAC CHANGES IN EQUINE ASTHMA
Date: Sunday, April 9, 2017
Horse Times Egypt: Equestrian Magazine :News :CARDIAC CHANGES IN EQUINE ASTHMA

Right ventricular function during acute exacerbation of severe equine asthma

 

Decloedt, H. Borowicz, M. Slowikowska, K. Chiers, G. Van Loon and A. Niedzwiedz

 

 

This prospective study aimed to identify changes to the structure and function of the right heart associated with an acute exacerbation of equine asthma. Six horses with a history of severe equine asthma were used, which were in remission at the beginning of the study. An acute episode of equine asthma was experimentally induced via exposure to straw and mouldy hay for 7 days. Horses were then returned to a dust-free environment and treated with daily intravenous dexamethasone until resolution of clinical signs.

 

All horses developed clinical signs within 2 days. Clinical and endoscopy scores were higher in horses following allergen exposure compared to pre-exposure and PaO2 and pH were lower. Cardiac biomarkers did not change. Following exposure, significant increases in right atrial, right ventricular and mean pulmonary artery pressure measurements were demonstrated. The highest pressures were found in horses with the highest clinical and endoscopic scores, likely reflecting increased severity of disease. When echocardiographic measurements in the experimental group were compared to healthy controls, significant differences in several measurements were found including greater right ventricular wall thickness in the disease group suggesting hypertrophy due to right ventricular pressure overload. Neutrophil infiltration and interstitial fibrosis were noted in myocardial biopsies from three of six horses, providing evidence of myocardial inflammation and remodelling in response to pressure overload.

 

 

Bottom line:

 

Equine asthma results in pulmonary hypertension and secondary changes to the right side of the heart, related to pressure overload.

 

 

--Ends--

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