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Horse Times Magazine :: Spring Issue # 53

PUBLISHED SPRING 2017, ISSUE 53 FEATURES:

20TH ANNIVERSARY
HRH PRINCESS HAYA BINT AL HUSSEIN

20TH ANNIVERSARY
RIDERS’ PROFILES

20TH ANNIVERSARY
BLUE BLOOD ADDICTED TO HORSES

20TH ANNIVERSARY
BEHIND THE SCENES

20TH ANNIVERSARY
CELEBRITIES WITH PASSION FOR HORSES

20TH ANNIVERSAR..

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Horse Times Weekly Headlines :: Issue # 28

• LGCT CANNES CSI5*: A SPECTACULAR WIN FOR LORENZO DE LUCA

• ATHINA ONASSIS HORSE SHOW CSI5* CHRISTIAN AHLMANN WINS THE LONGINES GP

• WARD AND ROTCHILD RECLAIM VICTORY IN SAPPHIRE GRAND PRIX DEVON CSI4*

• LGCT GRAND PRIX CANNES: MOYA WINS AND SMOLDERS HITS RANKING LEAD

• FEI NATIONS CUP..

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>> CARDIAC CHANGES IN EQUINE ASTHMA
Date: Sunday, April 9, 2017
Horse Times Egypt: Equestrian Magazine :News :CARDIAC CHANGES IN EQUINE ASTHMA

Right ventricular function during acute exacerbation of severe equine asthma

 

Decloedt, H. Borowicz, M. Slowikowska, K. Chiers, G. Van Loon and A. Niedzwiedz

 

 

This prospective study aimed to identify changes to the structure and function of the right heart associated with an acute exacerbation of equine asthma. Six horses with a history of severe equine asthma were used, which were in remission at the beginning of the study. An acute episode of equine asthma was experimentally induced via exposure to straw and mouldy hay for 7 days. Horses were then returned to a dust-free environment and treated with daily intravenous dexamethasone until resolution of clinical signs.

 

All horses developed clinical signs within 2 days. Clinical and endoscopy scores were higher in horses following allergen exposure compared to pre-exposure and PaO2 and pH were lower. Cardiac biomarkers did not change. Following exposure, significant increases in right atrial, right ventricular and mean pulmonary artery pressure measurements were demonstrated. The highest pressures were found in horses with the highest clinical and endoscopic scores, likely reflecting increased severity of disease. When echocardiographic measurements in the experimental group were compared to healthy controls, significant differences in several measurements were found including greater right ventricular wall thickness in the disease group suggesting hypertrophy due to right ventricular pressure overload. Neutrophil infiltration and interstitial fibrosis were noted in myocardial biopsies from three of six horses, providing evidence of myocardial inflammation and remodelling in response to pressure overload.

 

 

Bottom line:

 

Equine asthma results in pulmonary hypertension and secondary changes to the right side of the heart, related to pressure overload.

 

 

--Ends--

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